PDLLA Fillers

Beatrice Restore

Volume Restoration & Wrinkle Correction · Collagen Biostimulation

A PDLLA biostimulatory filler for facial volume loss and moderate-to-severe wrinkles such as the nasolabial folds. By stimulating collagen regeneration, it progressively restores tissue volume and reduces wrinkles.

  • Collagen-regeneration driven — naturally restores tissue volume and improves wrinkles such as the nasolabial folds
  • Autologous collagen rebuild — longer-lasting results
  • Uniform microspheres — stable, durable results with low nodule risk
Content 260 mg
Particle Size 25–50 μm
Presentation Vial
Store below 30 °C · ambient transport
Full Specifications

Technical Data at a Glance.

CompositionPDLLA microspheres, carboxymethylcellulose sodium (CMC)
Content260 mg per vial
Microsphere Size25–50 μm
PresentationVial (lyophilised powder)
IndicationsFor filling moderate-to-severe wrinkles such as the nasolabial folds, and for improving volume deficiency in the cheek area.
Duration12–18 months
Storage & TransportStore below 30 °C at ambient temperature; transport at ambient temperature
Diagram — mechanism of action

Mechanism of Action

Following deep dermal or subcutaneous injection, PDLLA microspheres gradually degrade and activate fibroblasts, promoting the regeneration of Type I and III collagen and elastin. This progressively restores facial tissue volume while improving wrinkles and skin elasticity.

Technical Advantage

Technical Advantage

Compared with PLLA and PCL, PDLLA microspheres have an amorphous structure that offers superior flexibility and resistance to brittle fracture. This allows them to adapt more effectively to dynamic facial tissue movement, supporting a more natural tissue feel and filling performance.

Clinical Cases

Before & After

Real patient photography from a Beatrice Restore treatment — drag the divider to compare.

After — Beatrice Restore Before — Beatrice Restore
Before After

Nasolabial Fold Volume Restoration

A Beatrice Restore treatment for the nasolabial folds, using PDLLA microspheres reconstituted with water for injection.

  • SubjectFemale · 26 years
  • RegionNasolabial folds
  • ProductBeatrice Restore
  • Dosage260 mg, reconstituted with water for injection

Illustrative clinical case — individual results may vary.

Clinical Evidence

Measured Results.

At 12 months post-treatment, the effective improvement rate for moderate-to-severe nasolabial fold wrinkles reached 81.52%.

81.52%
12-Month Efficacy — Nasolabial Folds

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