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Volume Restoration & Wrinkle Correction · Collagen Biostimulation
A PDLLA biostimulatory filler for facial volume loss and moderate-to-severe wrinkles such as the nasolabial folds. By stimulating collagen regeneration, it progressively restores tissue volume and reduces wrinkles.
| Composition | PDLLA microspheres, carboxymethylcellulose sodium (CMC) |
|---|---|
| Content | 260 mg per vial |
| Microsphere Size | 25–50 μm |
| Presentation | Vial (lyophilised powder) |
| Indications | For filling moderate-to-severe wrinkles such as the nasolabial folds, and for improving volume deficiency in the cheek area. |
| Duration | 12–18 months |
| Storage & Transport | Store below 30 °C at ambient temperature; transport at ambient temperature |
Following deep dermal or subcutaneous injection, PDLLA microspheres gradually degrade and activate fibroblasts, promoting the regeneration of Type I and III collagen and elastin. This progressively restores facial tissue volume while improving wrinkles and skin elasticity.
Compared with PLLA and PCL, PDLLA microspheres have an amorphous structure that offers superior flexibility and resistance to brittle fracture. This allows them to adapt more effectively to dynamic facial tissue movement, supporting a more natural tissue feel and filling performance.
Real patient photography from a Beatrice Restore treatment — drag the divider to compare.
A Beatrice Restore treatment for the nasolabial folds, using PDLLA microspheres reconstituted with water for injection.
Illustrative clinical case — individual results may vary.
At 12 months post-treatment, the effective improvement rate for moderate-to-severe nasolabial fold wrinkles reached 81.52%.
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